Description
ChemicalBook > CAS DataBase List > N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

Description
Product Name
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
CAS No.
132172-61-3
Chemical Name
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
Synonyms
DOTAP;DOTMA;dotap chloride;1,2-dioleoyl-3-trimethylammonium-propane (chloride salt);NSC8484;NSC 8484;NSC-8484;DOTAP-Cl;Lipofectin;18:1 TAP (DOTAP)
CBNumber
CB4441795
Molecular Formula
C42H80ClNO4
Formula Weight
698.56
MOL File
132172-61-3.mol
More
Less

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Property

Melting point:
35-38°C
storage temp. 
-20°C
solubility 
Chloroform (Slightly)
form 
lyophilized powder
color 
White to Pale Yellow
Stability:
Store in Freezer, Hygroscopic
InChIKey
KSXTUUUQYQYKCR-LQDDAWAPSA-M
SMILES
C(C[N+](C)(C)C)(COC(=O)CCCCCCC/C=C\CCCCCCCC)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Cl-]
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D6182
Product name
DOTAP chloride
Purity
≥98% (TLC), powder
Packaging
50mg
Price
$463
Updated
2024/03/01
Sigma-Aldrich
Product number
D6182
Product name
DOTAP chloride
Purity
≥98% (TLC), powder
Packaging
250mg
Price
$1840
Updated
2024/03/01
Cayman Chemical
Product number
15110
Product name
1,2-Dioleoyl-3-trimethylammoniumpropane (chloride)
Purity
≥95%
Packaging
50mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
15110
Product name
1,2-Dioleoyl-3-trimethylammoniumpropane (chloride)
Purity
≥95%
Packaging
100mg
Price
$138
Updated
2024/03/01
Cayman Chemical
Product number
15110
Product name
1,2-Dioleoyl-3-trimethylammoniumpropane (chloride)
Purity
≥95%
Packaging
250mg
Price
$288
Updated
2024/03/01
More
Less

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Chemical Properties,Usage,Production

Description

DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a potent cationic lipid widely used as a liposomal transfection reagent. DOTAP is also a strong activator of the innate immune system in animal cells and could serve as a potential candidate for the study of elicitors of plant immunity.

Description

DOTAP, 1,2-Dioleoyl-3-trimethylammonium propane is a di-chain, or gemini, cationic surfactant. DOTAP has been used for in vitro and in vivo nucleic acid and protein delivery.

Chemical Properties

White Foam

Uses

Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of DNA. Facilitates fusion of the complex with the plasma membrane of tissue culture cells, resulting in both uptake and

Uses

1,2-dioleoyloxy-3-(trimethylammonium)propane (DOTAP) chloride has been used for the preparation of cationic liposome and liposome-DNA complex. It has also been used to assess tumor necrosis factor α (TNF- α) production.

Biochem/physiol Actions

18:1 TAP (DOTAP) is a cationic lipid structure, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP(1,2-dioleoyl-3-trimethylammonium-propane). 18:1 TAP (DOTAP) mediates gene knockdown technique in hematopoietic stem cells (HSCs).

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE Suppliers

Canada 1 China 117 India 1 Switzerland 2 United Kingdom 3 United States 10 Global 134
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
Protheragen-ING
Tel
+16313385890
Email
info@protheragen-ing.com
Country
United States
ProdList
1091
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
More
Less

View Lastest Price from N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE 132172-61-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE 132172-61-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Shochem(Shanghai) Co.,Ltd
Product
DOTAP chloride 132172-61-3
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%MIN
Supply Ability
5KG/MONTH
Release date
2020-04-27

132172-61-3, N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDERelated Search:

Cholesterol PG?(egg?PC) Cholesteryl sodium sulfate Egg phospholipids Sodium hyaluronate DODMA DOTAP Ammonium chloride DOTAP MESYLATE, 98 N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE,N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE,DOTAP CHLORIDE SALT,DOTAP DOTAP DOTAP methyl sulfate,DOTAP,DOTAP METHOSULFATE DOTAP MESYLATE DOTAP METHYL SULPHATE SALT DOTAP DOTAP(OH) MESYLATE DOTAP acetate DOTAP(OH)2 MESYLATE

  • 1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE, CHLORIDE
  • DOTMA
  • DOTAP CHLORIDE SALT
  • DOTAP
  • dotap chloride
  • N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
  • N-[1-(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYL-AMMONIUM CHLORIDE SALT
  • N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE
  • TRIMETHYL[2,3-(DIOLEYLOXY)PROPYL]AMMONIUM CHLORIDE
  • 2,3-Bis(oleoyloxy)-N,N,N-trimethyl-1-propanaminium
  • 3-(Trimethylaminio)propane-1,2-diol 1,2-bis[(Z)-9-octadecenoate]
  • Lipofectin
  • N-[2,3-Bis(oleoyloxy)propyl]-N,N-dimethylmethanaminium
  • N-[2,3-Di(oleoyloxy)propyl]-N,N,N-trimethylaminium
  • N,N,N-TriMethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-1-propanaMiniuM
  • DOTAP;DOTAP, CHLORIDE
  • 1,2-dioleoyl-3-trimethylammonium-propane (chloride salt)
  • 18:1 TAP (DOTAP)
  • 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium
  • (2，3-Dioleyl-propyl) -trimethylamine
  • N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride
  • 1-Propanaminium, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecenyl]oxy]-, chloride (1:1)
  • NSC 8484
  • NSC8484
  • NSC-8484
  • DOTAP-Cl
  • 132172-61-3
  • C42H80ClNO4
  • C40H80ClNO2
  • Ammonium Chlorides (Quaternary)
  • Quaternary Ammonium Compounds
  • BioChemical
  • Cloning and Expression
  • Molecular Biology
  • Transfection & Transformation
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Mixed Fatty Acids